Drug Discovery & Organic Synthesis Lab
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E-mail : hongorg@kaist.ac.kr Tel : +82-42-350-2811 Web: http://ddnpslab.kaist.ac.kr Office : Room 4103, Department of Chemistry (Bldg E6-4), KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Korea Lab : Room 4118, (+82-42-350-2851, 5811)
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183. Concurrent Optimizations of Efficacy and Blood-Brain Barrier Permeability in New Macrocyclic LRRK2 Inhibitors for Potential Parkinson's Disease TherapeuticsKim, K.; Jang, A.; Shin , H. C.; Ye, I. ; Lee, J. E.; Kim, T.; Park, H.*; Hong, S.*J. Med. Chem. 2024, in press.
182. Nickel-Catalyzed Hydrofluorination in Unactivated Alkenes: Regio-and Enantioselective C–F Bond FormationLee, C.; Kim, M.; Han, S.; Kim, D.; Hong, S.*J. Am. Chem. Soc. 2024, 146, 9375.
181. Unraveling the Potential of Vinyl Ether as an Ethylene Surrogate in Heteroarene C–H Functionalization via the Spin-Center ShiftChoi, W.; Kim, L.; Hong, S.*Adv. Sci. 2024, 2309800.
180. Visible Light-Induced Enantioselective Radical Reactions Catalyzed by Redox-Active Chiral Lewis AcidsCao, S.; Hong, S.* ChemCatChem 2024, e202301606.
179. NiH-Catalyzed C–N Bond Formation: Insights and Advancements in Hydroamination of Unsaturated Hydrocarbons Lee, C.; Kang, H.-J.; Hong, S.* Chem. Sci. 2024, 15, 442.
178. Photocatalytic Enantioselective Hydrosulfonylation of α,β-Unsaturated Carbonyls with Sulfonyl Chlorides Cao, S.; Kim, D.; Lee, W.; Hong, S.*Angew. Chem. Int. Ed. 2023, 62, e202312780.
177. Three-Component Cyclobutylation via Silver(I)-Catalyzed Carbene Transfer Reactions with [1.1.1]Propellane Shin, S.; Kim, Y.; Hong, S.*ACS Catal. 2023, 13, 13325.
176. Nucleophilic C4-Selective (Hetero)Arylation of Pyridines for Facile Synthesis of HeterobiarylsKim, K.; You, E.; Hong, S.*Front. Chem. 2023, 11, 1254632 (Invited Article).
175. Regio- and Enantioselective Catalytic δ-C–H Amidation of Dioxazolones Enabled by Open-Shell Copper-Nitrenoid TransferKim, S.; Song, S. L.; Zhang, J.; Kim, D.; Hong, S.; Chang, S.*J. Am. Chem. Soc. 2023, 145, 16238.
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